Table 3.

Competing risk (CR) regression models identifying IHC staining patterns associated with refractory- or relapse-related death. ¹ Event of interest: refractory-related death, competing event: relapse-related death, ² event of interest: relapse-related death, competing event: refractory-related death, ³ subhazard ratio, ⁴ confidence interval based on robust variance estimates, ⁵ confidence interval based on bootstrap resampling (500 replicates), ⁶ CYCLON extra-nucleolar ⁽⁺⁾ versus CYCLON extra-nucleolar ⁽⁻⁾ staining, ⁷ NPM1 pan-cellular ⁽⁺⁾ versus NPM1 pan-cellular ⁽⁻⁾, ⁸ R-IPI high versus low score.

Competing Risk (CR)	Refractory 1				Relapse 2
	sHR 3	95%CI 4	p	Bs-95%CI 5	sHR	95%CI 4	p
CYCLON 6	4.04	1.62–10.05	0.003	1.32–12.09	1.08	0.24–4.92	0.92
NPM1 7	4.64	1.79–12.04	0.002	1.08–14.46	1.63	0.29–9.29	0.58
R-IPI 8	2.8	1.03–7.59	0.043	1.008–10.24	10.03	1.07–94.6	0.043