Table 4.

Frequency of molecular alterations in ovarian and colorectal mucinous carcinomas .

	Primary Ovarian Mucinous Carcinomas	Primary Colorectal Mucinous Carcinomas
KRAS mutations	32–56% [50,51,52,53]	23–38% [55,56,57]
HER2 amplification	18% [54]	<1% [58]
BRAF mutations	0% [53]	14–28% [56,57,59]
TP53 mutation	26% [50]	20–48% [59,60]

Abbreviations: KRAS, V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog; HER2, human epithelial growth factor receptor 2; BRAF, V-raf murine sarcoma viral oncogene homolog B1; TP53, Tumor protein p53.