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. 2021 Nov 30;13(23):6045. doi: 10.3390/cancers13236045

Table 2.

Cell line characteristics and WNT mutation status.

Cells MS CIMP CIN WNT3a WNT5a LRP6 WIF1 ROR2 APC CTNNB1 LEF1 cJUN/AP1
HCT116 MSI + - wt wt W419R met R302H wt S45del wt Wt
SW480 MSS - + wt wt wt met wt Q1338 * wt wt Wt
SW620 MSS - + wt wt wt met wt Q1338 * wt wt Wt

MSI, microsatellite instability; MSS, microsatellite stability; CIMP, CpG Island methylator phenotype; CIN, chromosomal instability; wt, wild type, * SW480 and SW620 cell lines derived from the same patient [41,44,45,46,47].