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. 2021 Dec 3;13(23):6101. doi: 10.3390/cancers13236101

Table 3.

Diagnostic or prognostic value of PCAT6.

Tumor Types Expression Diagnostic or Prognostic Value Ref.
Bladder cancer Up Poor OS, and poor PFS, AUC > 0.8 [24]
Up Poor OS [21]
Cervical cancer Up Shorter OS and DFS [28]
Colorectal cancer Up Worse OS [30]
Up Poor OS [31]
Gastric cancer Up Worse prognosis [34]
Hepatocellular carcinoma Up Poor OS [36]
Up Poor OS and DFS [37]
Up Shorter OS [38]
Up Poor PFS [132]
Lung cancer Up Tissue PCAT6: AUC > 0.9, sensitivity 86.67–100%, specificity 78.57–96%Plasma PCAT6: a. LUAD: AUC = 0.9213, sensitivity 87.67%, specificity 97.44; b. LUSC: AUC = 0.9583, sensitivity 94.12%, specificity 100% [41]
Up Poor OS [40]
Up Poor OS [20]
Up Poor OS [43]
Osteosarcoma Up Shorter OS and PFS [44]
Up Shorter OS and PFS [45]
Ovarian cancer Up Poor OS, PFS and PPS [48]
Pancreatic ductal adenocarcinoma Up Worse OS [51]
Prostate cancer Up Shorter overall and BM-free survival, shorter DFS [53]

OS, overall survival; PFS, progression-free survival; AUC, area under curve; DFS, disease-free survival; PPS, post progression survival.