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. 2021 Nov 25;12:774780. doi: 10.3389/fimmu.2021.774780

Table 3.

Main results regarding clinical outcomes of included studies.

Author (year) Thymectomized patients compared to controls P value
Silva et al. (2017a) (6) No allergy or autoimmunity
Van den Broek et al. (2017) (7) No autoimmunity
Gudmundsdottir et al. (2016) (9) > report of infections and allergies a
Kurobe et al. (2013) (19) ↑ frequency of hospital admission <0.02
Cao et al. (2011) (20) ↑ mean duration of antibiotic use (sub-total Tx vs controls)
14.1 days (±3.5) b vs 9.9 days (±3.1) b
<0.01
Van Gent et al. (2011) (16) No report of infections
Prelog et al. (2009) (23) > report of infections a ; NSS autoimmunity or cancer
Sauce et al. (2009) (24) NSS hospital admission or infection
Mancebo et al. (2008) (21) NSS infection, allergy, autoimmunity or cancer
Torfadottir et al. (2006) (15) > report of allergies, psoriasis and acute otitis media a
Eysteinsdottir et al. (2004) (31) No report of diseases
Wells et al. (1998) (22) NSS hospital admission or infection
Brearley et al. (1987) (3) > report of post-operative infections a

NSS, not statistically significant; Tx, thymectomy.

a

Did not perform statistical analysis.

b

Results are shown as mean ± standard deviation in brackets.

↑, higher.