Table 5.
Main results regarding numbers of TRECs of included studies.
| Author (year) | Thymectomized patients compared to controls | P value |
|---|---|---|
| Silva et al. (2017a) (6) | 0.52* (0.05-1.8) a vs 17.2* (4.01-39.3) a | 0.001 |
| Silva et al. (2017b) (28) | ↓ VLT and LT vs controls | <0.0001 (VLT); 0.004 (LT) |
| Gudmundsdottir et al. (2016) (9) | Nondetectable values in 10 out of 11 individuals | <0.01 |
| Zlamy et al. (2016) (29) | Detectable values in 14.7% vs 82.4% | 0.001 |
| Cao et al. (2011) (20) | ↓ levels after sub-total Tx compared to levels before surgery | <0.01 |
| Van Gent et al. (2011) (16) | ↓ numbers (in the first 5 years after Tx) NSS numbers (5 years after Tx) |
<0.001 |
| Prelog et al. (2009) (23) | 1275** (525-3616)
a
vs 5410** (2056-11,194)
a
(in individuals > 12 years old) |
<0.001 |
| Mancebo et al. (2008) (21) | ↓ levels after 6, 12, 18, 24 and 36 months after Tx | <0.01 |
| Halnon et al. (2005) (26) | ↓ numbers in subjects who had undergone surgical procedure compared to those who had no prior surgery | <0.0001 (no residual thymus); <0.001 (with residual thymus) |
LT, low TRECs; NSS, not statistically significant; Tx, thymectomy; VLT, very low TRECs.
a
Results are shown as median and ranges in brackets.
*TRECs/μL.
**TRECs per 105 CD4+CD45RA+CD62L+ T cells.
↓, lower.