Table 7.

Main results regarding levels of other markers of included studies.

Author (year)	Thymectomized patients compared to controls	P value
Silva et al. (2017a) (6)	NSS CTLA-4, CD39+	–
Silva et al. (2017b) (28)	↓ % and absolute count CD31+ in naïve CD4+ of VLT ↑ Bcl-2 in naïve CD4+ of VLT and LT	<0.0001 (%) and 0.0001 (absolute) 0.0187 (VLT) and 0.0487 (LT)
Van den Broek et al. (2017) (7)	Normal % CD31+ in naive Tcells >9 years after Tx	No comparison to controls
Gudmundsdottir et al. (2016) (9)	↓ % CD31+ in naive CD4+ (55% vs 81%)	0.034
Van den Broek et al. (2016) (10)	↓ % CD31+ in naïve CD4+ 1-5 years and >10 years after Tx	<0.05
Zlamy et al. (2016) (29)	↓ % CD31+ in CD8+, ↓ % CD127+ of naïve CD8+, ↑ % CD103+CD8+ in lymphocytes	0.03, 0.04, 0.05
Elder et al. (2015) (18)	NSS % PD1+, CD57+, CD27-, CD28- in CD8+	–
Schadenberg et al. (2014) (25)	↓ % CD31+ in Treg cells	<0.05
Sauce et al. (2012) (27)	Inverse correlation between % of CD31+ and Ki67 in naïve CD4+	<0.0001
Eysteinsdottir et al. (2009) (30)	NSS % CD127+ in Treg cells	–
Sauce et al. (2009) (24)	↓ % CD31+ in naive CD4+, NSS % CD57+ in memory T cells	<0.0001

LT, low TRECs; NSS, not statistically significant; Tx, thymectomy; VLT, very low TRECs.

↑, higher; ↓ lower.