FIGURE 3.
LINC01679 regulated cell proliferation, apoptosis, migration, and invasion in vitro. (A) qRT-PCR assay was conducted to detect LINC01679 expression in PCa patients. (B) KM survival analysis on high and low LINC01679 expression. (C) LINC01679 levels within PCa cells measured by qRT-PCR assay. LINC01679 expression (D,L), cell viability (E,F,M,N), cell apoptosis (G,O), proliferation (H,P), invasion (I,Q), migration (J,R), and protein expression of VEGF, Ki67, Bax, Bcl-2, MTA1, and MMP-2 (K,S) of cells transfected with siRNA-LINC01679 or LINC01679-expressing vector determined by qRT-PCR, CCK-8, flow cytometry, colony formation, Transwell, scratch, and WB assays. The experiment was repeated thrice independently; ** vs. NC or vector group, p < 0.01; ✣✣ vs. vector at 24 h group; †† vs. vector at 48 h group.