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. 2021 Nov 25;13(23):5937. doi: 10.3390/cancers13235937

Figure 7.

Figure 7

Orai3 controls migration of Panc1 cells. Scratch wound healing (A–C) and transwell migration assays (D–F) were performed for evaluating the role of Orai3 in regulating Panc1 migration. (A) Representative wound healing images at 0, 6, 12 and 24 h time points in the case of shNT Panc1 stable cells. (B) Representative wound healing images at 0, 6, 12 and 24 h time point in case of shOrai3 Panc1 stable cells. (C) Quantitative analysis of %wound healing over the period of 24 h in shNT and shOrai3 Panc1 stable cells from 4 independent experiments. (D) Representative micrographs of crystal violet stained transwell migrated shNT Panc1 stable cell line. (E) Representative micrographs of crystal violet stained transwell migrated shOrai3 Panc1 stable cells. (F) Quantitative analysis of number of migrated cells in the transwell migration assay from three independent experiments. Data presented as mean ± S.E.M. Unpaired Student’s t-test was performed for statistical analysis. p-value < 0.05 was considered as significant and p-value < 0.01 is denoted as “**”.