Table 1.
Clinical characteristics in 130 multiple myeloma patients at diagnosis.
| Age | |
|---|---|
| median in years (range) | 64 (31–80) |
| <65 years, N (%) | 74 (57) |
| 65–75 years, N (%) | 47 (36) |
| >75 years, N (%) | 9 (7) |
| Gender | |
| male, N (%) | 73 (56) |
| female, N (%) | 57 (44) |
| Time of diagnosis | |
| years 2000–2005, N (%) | 10 (8) |
| years 2006–2010, N (%) | 30 (23) |
| years 2011–2015, N (%) | 63 (48) |
| years 2016–2019, N (%) | 27 (21) |
| CRAB criteria (130 patients) | |
| anemia (Hb < 10 g/dL) | 64 (49) |
| bone lesions (>1 lesion) | 120 (92) |
| renal insufficiency (Creatinine > 2 mg/dL) | 10 (8) |
| hypercalcemia (>11.5 mg/dL) | 10 (8) |
| LDH (99 patients) | |
| normal | 84 (85) |
| elevated | 15 (15) |
| FISH risk stratification (57 patients) | |
| standard | 46 (81) |
| high | 11 (19) |
| R-ISS staging (60 patients) | |
| stage I-II | 48 (80) |
| stage III | 12 (20) |
| Extramedullary disease (130 patients) | |
| no | 126 (97) |
| yes | 4 (3) |
Abbreviations: LDH—lactate dehydrogenase; FISH—fluorescent in-situ hybridization; R-ISS—revised international staging system.