Table 2.
The impact of occurrence of missing teeth on risk of developing head and neck squamous cell carcinoma.
| References | Year | Rated Factor | Type of Study | n | Risk of HNC | Description |
|---|---|---|---|---|---|---|
| Pereira et al. [36]. | 2020 | missing teeth (6 or more) |
case-control study | 899 cases 899 controls |
Increased (in the group with missing teeth) |
OR = 3.30; 95% CI: 2.67—4.08 |
| Gupta et al. [37]. | 2020 | missing teeth (5 or more) |
case-control study | 240 cases 240 controls |
Increased (in the group with missing teeth) |
OR = 3.24; 95% CI: 2.09—5.01 |
| Kawakita et al. [38]. | 2017 | missing teeth (5 or more) |
case-control study | 484 cases 313 controls |
Increased (in the group with missing teeth) |
OR = 2.68; 95% CI: 2.09—3.43 |
| Liu et al. [39]. | 2016 | missing teeth a—1—3 missing teeth b—4—13 missing teeth c—more than 14 |
case-control study | 2528 cases 2596 controls |
Statistically insignificant * |
a—OR = 0.97; 95% CI: 0.79, 1.19 b—OR = 0.98; 95% CI: 0.76, 1.28 c—OR = 0.71; 95% CI: 0.46, 1.11 |
| Chang et al. [33]. | 2013 | missing teeth a—1—10 missing teeth b—11—20 missing teeth c—more than 20 |
case-control study | 317 cases 296 controls |
Increased (in the group with missing teeth) |
a— OR = 1.15; 95% CI: 0.61–2.20 b— OR = 1.34; 95% CI: 0.58–3.07 c— OR = 2.40; 95% CI: 0.97–5.97 |
OR—odds ratio, CI—confidence intervals; HNC—head and neck squamous cell carcinoma; * the study concerned only nasopharyngeal neoplasms.