Table 2.
Important studies evaluating the role of surgery in ependymoma patients. IT: infratentorial; ST: supratentorial. GTR: gross total resection; STR: subtotal resection; y = years; NA = not available.
| Study | N. | Location | Grading | EOR | OS | PFS |
|---|---|---|---|---|---|---|
| Varma, 2018 [50] | 13 | IT 61.5% ST 38.5% |
I | GTR 92% STR 8% | NA | NA |
| Song, 2017 [15] | 53 | IT 64.2% ST 35.8% |
II 66% III 34% |
GTR 54.7% STR 45.3% | 5 y 82.5%, 10 y 75.7% |
NA |
| Dutzmann 2013 [5] | 64 | IT 35.6% ST 34.4%, |
I 28.1% II 51.6% III 20.3% |
GTR 76.6% | NA | NA |
| Metellus, 2010 [47] | 114 | IT 80.7% ST 19.3% |
II | GTR 58.7%, STR 41.3% | 5 y 86% 10 y 81% |
5 y 74.6% 10 y 58.9% |
| Vitanovics, 2009 [51] | 61 | IT 51% ST 49% |
II 65.5% III 34.5% |
GTR 60% STR 40% | NA | NA |
| Figarella-Branger, 2007 [13] | 216 | IT 66% ST 34% |
II 73% III 27% |
NA | NA | NA |
| Metellus, 2007 [12] | 152 | IT 70% ST 30% |
II 72% III 28.3% |
GTR 58.6% STR 41.4%, | 5 y 84.8% 10 y 76.5% |
5 y 63.5% 10 y 52.8% |
| Metellus, 2007 [49] | 121 | IT 66% ST 34% |
II 72.7% III 27.3% |
GTR 63% STR 37% | 5 y 85% 10 y 76% |
NA |
| Reni, 2003 [52] | 70 | IT 44% ST 56% |
II 77% III 23% |
GTR grade II 63% GTR grade III 47% |
5 y 67% 10 y 50% |
NA |
| Donahue, 1998 [53] | 10 | IT 80% ST 20% |
not specified | GTR 10% STR 90% | NA | NA |