Table 3.
Logistic regression analysis of clinical factors affecting the success rate of next-generation sequencing using specimens obtained through EBUS-TBNA.
| Variables | Univariable Analysis | Multivariable Analysis | ||
|---|---|---|---|---|
| Success Cases/All Cases (%) | p Value † | Odds Ratio (95 %CI) | p Value ‡ | |
| Needle size | 0.79 | - | - | |
| 25-gauge | 23/28 (82.1) | |||
| 22-gauge | 107/128 (83.6) | |||
| Systemic staging | 1.0 | - | - | |
| Performed | 41/49 (83.7) | |||
| Not performed | 89/107 (83.2) | |||
| Necrotic finding on CT | 0.52 | - | - | |
| Positive | 55/64 (85.9) | |||
| Negative | 75/92 (81.5) | |||
| B-mode categories | ||||
| Short axis, mm | 0.62 | - | - | |
| ≤10 | 32/37 (86.5) | |||
| >10 | 98/119 (82.4) | |||
| Shape | 0.82 | - | - | |
| Round | 42/51 (82.4) | |||
| Oval | 88/105 (83.8) | |||
| Margin | 0.63 | - | - | |
| Distinct | 97/115 (84.3) | |||
| Indistinct | 33/41 (80.5) | |||
| Echogenicity | 1.0 | - | - | |
| Heterogeneous | 128/154 (83.1) | |||
| Homogeneous | 2/2 (100) | |||
| Central hilar structure | 0.21 | - | - | |
| Presence | 11/11 (100) | |||
| Absence | 119/145 (82.1) | |||
| Coagulation necrosis sign | 1.0 | - | - | |
| Presence | 37/44 (84.1) | |||
| Absence | 93/112 (83.0) | |||
| Color/power Doppler images | 1.0 | - | - | |
| Vascular pattern II–III | 76/91 (83.5) | |||
| Vascular pattern 0–I | 54/65 (83.1) | |||
| Number of punctures | 0.004 | 1.67 (0.49–5.62) | 0.41 | |
| <4 | 17/27 (63.0) | |||
| ≥4 | 113/129 (87.6) | |||
| Number of core tissues | <0.001 | 3.39 (1.09–10.6) | 0.035 | |
| <4 | 34/50 (68.0) | |||
| ≥4 | 96/106 (92.5) | |||
Data are presented as number (%). † Calculated using Fisher’s exact test. ‡ Calculated using logistic regression analysis. CT, computed tomography.