Table 1.
Clinical characteristics of patients with RMC and matched control genitourinary malignancies.
| Variable | RMC (N = 71) | Matched (N = 122) | p Value |
|---|---|---|---|
| Age, median (IQR) | 29.6 (23.2–37.5) | 29.9 (23.8–39.6) | 0.5 |
| Biological sex, no. (%) | 0.7 | ||
| Male | 49 (69) | 87 (71) | |
| Female | 22 (31) | 35 (29) | |
| Race, no. (%) | <0.001 | ||
| African American | 61 (86) | 47 (39) | |
| White | 7 (10) | 66 (54) | |
| Hispanic | 2 (3) | 4 (3) | |
| Asian | 1 (1) | 5 (4) | |
| Sickle hemoglobinopathy, no. (%) | 71 (100) | 0 | <0.001 |
| Sickle cell trait | 70 (99) | ||
| Sickle beta-thalassemia | 1 (1) | ||
| Comorbidities, no. (%) | |||
| HTN | 12 (17) | 33 (27) | 0.2 |
| Other comorbidities | 8 (11) | 58 (48) | <0.001 |
| ECOG, no. (%) | <0.001 | ||
| 0 | 15 (21) | 78 (64) | |
| 1 | 42 (59) | 41 (34) | |
| 2 | 10 (14) | 2 (2) | |
| 3 | 4 (6) | 1 (1) | |
| BMI, median (IQR), kg/m2 | 27 (24.3–29.9) | 27.1 (23.9–31.6) | 0.7 |
| Albumin, median (IQR), g/dL | 4.3 (4–4.6) | 4.4 (4.1–4.6) | 0.3 |
| Smoking history, no. (%) | 15 (21) | 56 (46) | 0.001 |
| Exercise history, no. (%) | 36 (51) | 18 (15) | <0.001 |
| Athlete, no. (%) | 24 (34) | 5 (4) | <0.001 |
| Military, no. (%) | 7 (10) | 4 (3) | 0.005 |
| Activity index, no. (%) | 47 (66) | 20 (16) | <0.001 |