Table 4.
Adverse effects of TSD and MAD therapies reported after the 2-month treatment.
| Adverse Effects | TSD-Intolerant (n = 7/12)a | TSD Users (n = 26/27)b | MAD Users (n = 26/26) |
|---|---|---|---|
| Strong sensation in the tongue | 7 (100) | 17 (65.4) | 1 (3.8) |
| Excessive salivation | 7 (100) | 20 (76.9) | 10 (38.5) |
| Increased awakenings with OA use | 5 (71.4) | 15 (57.7) | 9 (34.6) |
| Discomfort because the device does not stay in place | 4 (57.1) | 20 (76.9) | 3 (11.5) |
| Dryness of mouth | 3 (42.9) | 15 (57.7) | 19 (73.1) |
| Discomfort or pain in oral soft tissues | 5 (71.4) | 12 (46.2) | 11 (42.3) |
| Tongue fatigue | 6 (85.7) | 12 (46.2) | 0 (0) |
| Difficulties swallowing with OA in place | 5 (71.4) | 14 (53.8) | 12 (46.2) |
| Difficulties falling asleep with OA | 5 (71.4) | 12 (46.2) | 8 (30.8) |
| Discomfort because of bulkiness of OA | 5 (71.4) | 11 (42.3) | 11 (42.3) |
| More unrested sleep with OA use | 5 (71.4) | 11 (42.3) | 7 (26.9) |
| Discomfort or pain in jaws | 2 (28.6) | 6 (23.1) | 16 (61.5) |
| Bite changes | 1 (14.3) | 6 (23.1) | 16 (61.5) |
| Discomfort or pain in teeth | 1 (14.3) | 7 (26.9) | 18 (69.2) |
| Device causes gagging | 1 (14.3) | 6 (23.1) | 2 (7.7) |
| Claustrophobia/breathing difficulties with OA in place | 4 (57.1) | 5 (19.2) | 1 (3.8) |
Values are presented as n (%). aFive patients did not fill our adverse effects form. bOne patient did not fill out adverse effects form. MAD = mandibular advancement device, OA = oral appliance, TSD = tongue-stabilizing device.