Table 2.
Sleep and respiratory parameters over time.
| Baseline | Mandibular Advancement Device | |||
|---|---|---|---|---|
| 3–6 Months | 2 Years | 5 Years | ||
| Apnea-hypopnea index, events/h | 26.4 [17.7–37.1] | 6.6 [3.0–12.9]a | 7.9 [3.8–16.1]a,b | 11.1 [6.1–17.3]a,d |
| Apnea index, /h | 8.3 [3.4–18.0] | 1.0 [0.2–3.6]a | 1.1 [0.3–3.8]a,b | 2.0 [0.4–5.8]a,c |
| Hypopnea index, /h | 15.0 [9.2–22.4] | 5.0 [2.0–9.7]a | 5.5 [2.4–10.9]a,d | 7.3 [4.0–13.0]a,e |
| Supine AHI, events/h | 32.9 [20.5–49.9] | 8.0 [3.0–16.6]a | 11.8 [3.2–21.6]a,b | 14.0 [5.8–25.0]a,e |
| Nadir SpO2, % | 84 [78–87] | 87 [83–90]f | 87 [84–89]b,f | 86 [82–88]c,f |
| Time with SpO2 < 90%, min | 6 [1–22] | 1 [0–9]f | 1 [0–6]f | 2 [0–11]f,g |
| ODI > 3%, /h | 17 [9–29] | 5 [2–11]a | 8 [3–15]a,d | 11 [5–17]a,e |
Values are median [interquartile range]. a P < .0001 vs baseline. b P < .05 vs 3–6 months. c P < .05 vs 2 years. d P < .001 vs 3–6 months. e P < .001 vs 2 years. f P < .01 vs baseline. g P < .01 vs 2 years. AHI = apnea-hypopnea index, ODI = oxygen desaturation index, SpO2 = oxygen saturation.