Table 4.
Significant predictors of therapy success (percentage of patients with a ≥50% decrease in AHI from baseline, model 1), complete response (AHI < 10 events/h, model 2), and long-term treatment continuation (model 3) on multivariate analysis.
| Odds Ratio (95% CI) | P | |
|---|---|---|
| Model 1 | ||
| Baseline AHI 15 to ≤ 30 events/h (moderate OSA vs mild OSA) | 3.49 (1.26–9.64) | .0190 |
| Baseline AHI ≥ 30 events/h (severe OSA vs mild OSA) | 4.74 (1.59–14.11) | .0190 |
| No previous CPAP therapy | 2.47 (1.25–4.88) | .0161 |
| Treatment success after 3- to 6-month follow-up | 3.99 (1.57–10.14) | .0161 |
| Model 2 | ||
| Body weight change (per 1-kg increase) | 0.88 (0.82–0.96) | .0033 |
| Dental class II (vs class I) | 5.61 (2.25–14.01) | .0011 |
| Baseline apnea index (per 1-event/h increase) | 0.95 (0.90–0.99) | .0188 |
| Model 3 | ||
| Self-reported sleep duration 7–8 h (vs ≤ 6 h) | 1.96 (1.12–3.45) | .0285 |
| MAD device renewal (yes vs no) | 4.65 (2.24–9.66) | <.0001 |
AHI = apnea-hypopnea index, CI = confidence interval, CPAP = continuous positive airway pressure, MAD = mandibular advancement device, OSA = obstructive sleep apnea.