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. 2021 Aug 1;17(8):1695–1705. doi: 10.5664/jcsm.9308

Table 4.

Significant predictors of therapy success (percentage of patients with a ≥50% decrease in AHI from baseline, model 1), complete response (AHI < 10 events/h, model 2), and long-term treatment continuation (model 3) on multivariate analysis.

Odds Ratio (95% CI) P
Model 1
 Baseline AHI 15 to ≤ 30 events/h (moderate OSA vs mild OSA) 3.49 (1.26–9.64) .0190
 Baseline AHI ≥ 30 events/h (severe OSA vs mild OSA) 4.74 (1.59–14.11) .0190
 No previous CPAP therapy 2.47 (1.25–4.88) .0161
 Treatment success after 3- to 6-month follow-up 3.99 (1.57–10.14) .0161
Model 2
 Body weight change (per 1-kg increase) 0.88 (0.82–0.96) .0033
 Dental class II (vs class I) 5.61 (2.25–14.01) .0011
 Baseline apnea index (per 1-event/h increase) 0.95 (0.90–0.99) .0188
Model 3
 Self-reported sleep duration 7–8 h (vs ≤ 6 h) 1.96 (1.12–3.45) .0285
 MAD device renewal (yes vs no) 4.65 (2.24–9.66) <.0001

AHI = apnea-hypopnea index, CI = confidence interval, CPAP = continuous positive airway pressure, MAD = mandibular advancement device, OSA = obstructive sleep apnea.