Table 2.

Association between CXCR4, PKC-δ and CD133 and clinicopathological factors.

		CXCR-4			PKC-δ			CD133
		Negative (18)	Positive (33)	p Value	Negative (21)	Positive (30)	p Value	Negative (22)	Positive (29)	p Value
No. of Patients
Age
≤60	26	12	14	p < 0.14	10	16	p < 0.77	8	18	p < 0.09
>60	25	6	19		11	14		14	11
Gender
Male	29	11	18	p < 0.77	15	14	p < 0.09	14	15	p < 0.56
Female	22	7	15		6	16		8	14
Stage
I–II	24	9	15	p < 0.78	14	10	p < 0.02 *	16	8	p < 0.001 *
III–IV	27	9	18		7	20		6	21
Lymph node Metastasis
Negative	23	15	8	p < 0.001 **	16	7	p < 0.001 **	15	8	p < 0.005 **
Positive	28	3	25		5	23		7	21
Histological Grade
Well Differentiated	8	6	2	p < 0.02 *	6	2	p < 0.10	7	1	p < 0.008 **
Moderately Differentiated	19	7	12		7	12		9	10
Poorly Differentiated	24	5	19		8	16		6	18
Location of the Tumours
Tongue	15	8	7	p < 0.42	7	8	p < 0.54	6	9	p < 0.56
Buccal	9	3	6		5	4		4	5
Palate	8	3	5		4	4		4	4
Gingiva	10	2	8		3	7		6	4
Floor of Mouth	9	2	7		2	7		2	7

Negative (0 and 1+ categories) and Positive (2+ and 3+ categories). * Statistically significant, ** Statistically highly significant.