Table 5.

Psychometric scores (PANSS, GAF, DES) at different times in the two groups, divided for CUD.

DUP < 1 year		CUD− (n = 15)	CUD+ (n = 16)	t	p
	PANSS—positive
	T0	26.00 ± 2.36	28.81 ± 4.78	−2.097	0.048
	T1	22.93 ± 3.75	27.13 ± 4.38	−2.853	0.008
	T2	20.13 ± 3.74	25.75 ± 3.99	−4.036	0.000
	PANSS—negative
	T0	20.40 ± 3.09	22.56 ± 3.44	−1.836	0.077
	T1	19.20 ± 2.37	21.00 ± 3.31	−1.732	0.094
	T2	18.53 ± 2.59	19.38 ± 2.87	−0.855	0.399
	PANSS—general
	T0	58.27 ± 8.44	60.06 ± 11.04	−0.506	0.617
	T1	53.93 ± 8.75	54.38 ± 10.75	−0.125	0.901
	T2	49.60 ± 10.53	50.81 ± 10.06	−0.328	0.745
	PANSS—total
	T0	104.67 ± 8.45	111.44 ± 13.21	−1.687	0.102
	T1	96.07 ± 9.00	102.50 ± 12.42	−1.642	0.111
	T2	88.27 ± 11.57	95.94 ± 11.06	−1.887	0.069
	GAF
	T0	50.67 ± 4.61	46.69 ± 4.44	2.449	0.021
	T1	54.40 ± 4.21	51.06 ± 3.89	2.296	0.029
	T2	59.80 ± 3.57	57.50 ± 4.38	1.596	0.121
	DES
	T0	25.53 ± 2.20	33.50 ± 6.00	−4.967	0.000
	T1	21.07 ± 3.08	31.00 ± 5.29	−6.330	0.000
	T2	19.73 ± 3.04	30.25 ± 5.09	−6.924	0.000
DUP ≥ 1 year		CUD− (n = 15)	CUD+ (n = 16)	t	p
	PANSS—positive
	T0	29.87 ± 5.30	32.38 ± 5.35	−1.310	0.201
	T1	27.47 ± 4.26	30.63 ± 5.14	−1.857	0.074
	T2	26.27 ± 5.08	29.94 ± 5.27	−1.972	0.058
	PANSS—negative
	T0	28.93 ± 3.65	24.69 ± 4.19	2.998	0.006
	T1	27.07 ± 4.08	23.13 ± 3.65	2.839	0.008
	T2	26.07 ± 3.77	23.06 ± 3.89	2.181	0.037
	PANSS—general
	T0	58.07 ± 6.24	58.13 ± 5.76	−0.027	0.979
	T1	53.47 ± 5.74	57.75 ± 7.45	−1.784	0.085
	T2	51.93 ± 5.76	55.50 ± 6.52	−1.609	0.118
	PANSS—total
	T0	116.87 ± 8.92	115.19 ± 8.00	0.552	0.585
	T1	108.00 ± 8.15	111.50 ± 11.02	−1.000	0.326
	T2	104.27 ± 7.60	108.50 ± 9.84	−1.334	0.193
	GAF
	T0	49.33 ± 5.19	47.38 ± 6.46	0.926	0.362
	T1	52.33 ± 4.91	48.69 ± 5.20	2.004	0.054
	T2	56.27 ± 3.24	53.19 ± 2.61	2.922	0.007
	DES
	T0	29.80 ± 5.19	38.50 ± 7.08	−3.881	0.001
	T1	28.53 ± 5.21	37.31 ± 7.56	−3.740	0.001
	T2	24.73 ± 4.76	35.25 ± 8.35	−4.270	0.000

Statistics: Student’s t-test; all results are reported as mean ± SD.