Table 2.
Remission Status | Number (%) |
---|---|
CR | 2 (6%) |
PR | 9 (25%) |
SD | 8 (22%) |
PD | 17 (47%) |
Bridging therapy given: Yes | 17 (47%) |
Radiotherapy | 4 (11%) |
Pharmacotherapy | 17 (47%) |
MATRIx | 1 (3%) |
R-GEMOX | 2 (6%) |
Ibrutinib | 4 (11%) |
Gemcitabine | 1 (3%) |
Bendamustine | 6 (17%) |
Polatuzumab vedotin | 4 (11%) |
Rituximab | 9 (25%) |
CAR-T-cell therapy type | |
Kymriah® (Novartis) | 26 (72%) |
Yescarta® (Gilead) | 10 (28%) |
Lymphodepleting chemotherapy | |
Fludarabine, Cyclophosphamide | 36 (100%) |
CAR-T: chimeric antigen receptor T cell; CR: complete remission; PR: partial remission; SD: stable disease; PD: progressive disease; MATRIx: methotrexate, cytarabine, thiotepa, and rituximab; R-GEMOX: gemcitabine, oxaliplatin, and rituximab.