Table 1.
Demographic data of patients with COVID-19 stratified by wave and cancer history. Data are shown as n (%) or median (IQR) unless otherwise specified. p-value significance level is indicated for the combined cancer and non-cancer cohort in each wave. Legend: BMI, body mass index; †, data shown as mean (standard deviation); * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.
| Wave 1 Control (n = 226) | Wave 1 Cancer (n = 94) | Wave 2 Control (n = 226) | Wave 2 Cancer (n = 113) | p-Value | |
|---|---|---|---|---|---|
| Male | 152 (67.3%) | 62 (66.0%) | 122 (54.0%) | 61 (54.0%) | *** |
| Median age(years) | 70.50 (60.00–80.00) | 71.00 (62.00–80.00) | 71.00 (58.00–79.00) | 71.00 (58.00–79.00) | |
| BMI | 26.59 (23.45–30.47) | 25.05 (21.72–30.48) | 26.71 (23.34–32.12) | 26.20 (22.37–30.48) | |
| South Asian | 28 (12.4%) | 8 (8.5%) | 42 (18.6%) | 18 (15.9%) | ** |
| Black | 37 (16.4%) | 6 (6.4%) | 29 (12.8%) | 10 (8.8%) | |
| Other | 19 (8.4%) | 9 (9.6%) | 17 (7.5%) | 13 (11.5%) | |
| White | 115 (50.9%) | 64 (68.1%) | 78 (34.5%) | 54 (47.8%) | ** |
| Ex or active smoker | 71 (31.4%) | 49 (52.1%) | 64 (28.3%) | 47 (41.6%) | |
| Cardiovascular disease |
59 (26.1%) | 18 (19.1%) | 57 (25.2%) | 19 (16.8%) | |
| Dementia | 35 (15.5%) | 7 (7.4%) | 17 (7.5%) | 7 (6.2%) | ** |
| Diabetes | 73 (32.3%) | 24 (25.5%) | 77 (34.1%) | 25 (22.1%) | |
| Congestive cardiac failure | 16 (7.1%) | 9 (9.6%) | 11 (4.9%) | 4 (3.5%) | |
| Liver disease | 4 (1.8%) | 3 (3.2%) | 5 (2.2%) | 0 (0.0%) | |
| Hypertension | 123 (54.4%) | 37 (39.4%) | 106 (46.9%) | 48 (42.5%) | |
| Peripheral vascular disease | 13 (5.8%) | 2 (2.1%) | 1 (0.4%) | 4 (3.5%) | * |
| Cerebrovascular disease | 37 (16.4%) | 12 (12.8%) | 12 (5.3%) | 14 (12.4%) | ** |
| Chronic lung disease | 47 (20.8%) | 14 (14.9%) | 51 (22.6%) | 16 (14.2%) | |
| Chronic kidney disease |
26 (11.5%) | 12 (12.8%) | 23 (10.2%) | 13 (11.5%) | |
| Ongoing corticosteroids | 13 (5.8%) | 4 (4.3%) | 2 (0.9%) | 3 (2.7%) | ** |
| Composite co-morbidity score † | 2.57 (1.71) | 2.79 (1.44) | 2.04 (1.33) | 2.81 (1.42) | * |
| COVID-19-specific therapy | 13 (5.8%) | 1(1.1%) | 134 (59.3%) | 37 (32.7%) | **** |
| Hospitalization | 223 (98.7%) | 86 (91.5%) | 179 (79.2%) | 82 (72.6%) | *** |
| Intensive care admission |
76 (33.6%) | 22 (23.4%) | 68 (30.1%) | 24 (21.2%) | |
| Death | 77 (34.1%) | 41 (43.6%) | 43 (19.0%) | 18 (15.9%) | *** |