Table 1.
Cohort characteristics by histology and sex.
| Patients’ Characteristics | Non-Squamous | Squamous | Unknown Histology | Overall n = 4393 (%) |
|||
|---|---|---|---|---|---|---|---|
| n = 2793 | n = 1559 | n = 41 | |||||
| Women n = 1057 (%) |
Men n = 1736 (%) |
Women n = 289 (%) |
Men n = 1270 (%) |
Women n = 13 (%) |
Men n = 28 (%) |
||
| Age at cohort entry date, mean (SD) | 67.5 (11.5) | 69.6 (9.7) | 70.7(9.0) | 71.8 (9.2) | 68.9 (11.1) | 70.6 (10.7) | 69.8 (10.1) |
| Age bands at cohort entry date | |||||||
| 18–54 | 144 (13.6) | 136 (7.8) | 17 (5.9) | 67 (5.3) | 2 (15.4) | 4 (14.3) | 370 (8.4) |
| 55–69 | 424 (40.1) | 671 (38.7) | 100 (34.6) | 395 (31.1) | 3 (23.1) | 6 (21.4) | 1599 (36.4) |
| 70–84 | 434 (41.1) | 856 (49.3) | 163 (56.4) | 732 (57.6) | 8 (61.5) | 15 (53.6) | 2208 (50.3) |
| 85+ | 55 (5.2) | 73 (4.2) | 9 (3.1) | 76 (6.0) | 0 | 3 (10.7) | 216 (4.9) |
| Time in the study cohort, median (IQR) |
338.0 (113, 685) |
211.0 (72, 533) |
201.0 (70, 424) |
228.0 (78, 444) |
400.0 (140, 750) |
134.0 (50, 370) |
239.0 (80, 540) |
| First-line pharmacotherapies | |||||||
| Standard chemotherapy | 526 (49.8) | 921 (53.1) | 151 (52.2) | 694 (54.6) | 6 (46.2) | 13 (46.4) | 2311 (52.6) |
| Target therapies | 158 (14.9) | 112 (6.5) | 3 (1.0) | 2 (0.2) | 4 (30.8) | 0 (0.0) | 279 (6.4) |
| Immunotherapy | 33 (3.1) | 52 (3.0) | 7 (2.4) | 19 (1.5) | 0 (0.0) | 0 (0.0) | 111 (2.5) |
| Unspecified anti-body therapy | 10 (0.9) | 23 (1.3) | 1 (0.3) | 12 (0.9) | 0 (0.0) | 0 (0.0) | 46 (1.0) |
| Radiotherapy only | 44 (4.2) | 105 (6.0) | 20 (6.9) | 84 (6.6) | 1 (7.7) | 2 (7.1) | 256 (5.8) |
| Untreated | 286 (27.1) | 523 (30.1) | 107 (37.0) | 459 (36.1) | 2 (15.4) | 13 (46.4) | 1390 (31.6) |
| Concomitant radiotherapy | 103 (9.7) | 151 (8.7) | 18 (6.2) | 59 (4.6) | 2 (15.4) | 0 | 333 (7.6) |
| Diagnostic imaging | |||||||
| Computed tomography | 745 (70.5) | 1280 (73.7) | 215 (74.4) | 973 (76.6) | 10 (76.9) | 15 (53.6) | 3238 (73.7) |
| Radiography | 509 (48.2) | 875 (50.4) | 154 (53.3) | 726 (57.2) | 7 (53.8) | 21 (75.0) | 2292 (52.2) |
SD: standard deviation; IQR: interquartile range.