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. 2021 Dec 3;13(23):6109. doi: 10.3390/cancers13236109

Table 2.

Association between pre-treatment BMI with irAEs (N = 684).

Pre-treatment BMI (kg/m2) Had irAEs/Total Rate (%) of irAEs and 95% CI cOR and 95% CI aOR and 95% CI
<25 115/322 35.7 (30.7, 41.1) REF REF
25 to <30 102/217 47.0 (40.0, 53.7) 1.60 (1.12, 2.27) 1.46 (1.02, 2.11)
≥30 71/145 49.0 (40.9, 57.0) 1.73 (1.16, 2.57) 1.47 (0.96, 2.23)
p-trend < 0.01 p-trend = 0.04

Abbreviations: aOR: adjusted odds ratio, BMI: body mass index, CI: confidence interval, cOR: crude odds ratio, irAEs: immune-related adverse events. The multivariable model adjusted for age, race, sex, smoking status, metastasis, and lines of therapy.