Table 2.
Pre-treatment BMI (kg/m2) | Had irAEs/Total | Rate (%) of irAEs and 95% CI | cOR and 95% CI | aOR and 95% CI |
---|---|---|---|---|
<25 | 115/322 | 35.7 (30.7, 41.1) | REF | REF |
25 to <30 | 102/217 | 47.0 (40.0, 53.7) | 1.60 (1.12, 2.27) | 1.46 (1.02, 2.11) |
≥30 | 71/145 | 49.0 (40.9, 57.0) | 1.73 (1.16, 2.57) | 1.47 (0.96, 2.23) |
p-trend < 0.01 | p-trend = 0.04 |
Abbreviations: aOR: adjusted odds ratio, BMI: body mass index, CI: confidence interval, cOR: crude odds ratio, irAEs: immune-related adverse events. The multivariable model adjusted for age, race, sex, smoking status, metastasis, and lines of therapy.