Table 2.

Best classifiers’ cross-validation and test set performances, as well as the difference between cross-validation and test set performance, $\mathsf{\Delta }$. The performance columns are colour coded from highest value in green, to lowest value in white. The $\mathsf{\Delta }$ columns are colour coded from lowest value in green to highest value in red.

Model	cv_F2	ts_F2	cv_Kappa	ts_Kappa	cv_AUC	ts_AUC	cv_AUPRC	ts_AUPRC	$\mathsf{\Delta }$ F2	$\mathsf{\Delta }$ Kappa	$\mathsf{\Delta }$ AUC	$\mathsf{\Delta }$ AUPRC
G_D_SVM-RFE_LR	0.826	0.745	0.555	0.416	0.765	0.772	0.68	0.518	0.081	0.139	−0.007	0.162
G_D_SVM-RFE_RF	0.859	0.618	0.657	0.333	0.857	0.843	0.787	0.734	0.241	0.324	0.014	0.053
G_D_SVM-RFE_XGB	0.868	0.729	0.655	0.354	0.859	0.753	0.792	0.545	0.139	0.301	0.106	0.247
G_S_SVM-RFE_LR	0.831	0.652	0.528	0.32	0.798	0.766	0.742	0.655	0.179	0.208	0.032	0.087
G_S_SVM-RFE_DT	0.868	0.611	0.584	0.301	0.806	0.746	0.545	0.449	0.257	0.283	0.06	0.096
G_S_SVM-RFE_RF	0.862	0.737	0.629	0.385	0.873	0.788	0.841	0.576	0.125	0.244	0.085	0.265
G_S_SVM-RFE_XGB	0.849	0.684	0.551	0.308	0.847	0.728	0.805	0.504	0.165	0.243	0.119	0.301
G_D_mRMR_LR_EN	0.812	0.638	0.557	0.26	0.789	0.755	0.724	0.53	0.174	0.297	0.034	0.194
G_D_mRMR_DT	0.836	0.632	0.556	0.231	0.767	0.634	0.636	0.404	0.204	0.325	0.133	0.232
G_D_mRMR_RF	0.827	0.488	0.636	0.385	0.789	0.757	0.683	0.737	0.339	0.251	0.032	−0.054
G_D_mRMR_XGB	0.84	0.575	0.576	0.314	0.808	0.719	0.718	0.485	0.265	0.262	0.089	0.233
G_S_mRMR_DT	0.884	0.722	0.554	0.325	0.778	0.691	0.405	0.271	0.162	0.229	0.087	0.134
G_S_mRMR_RF	0.853	0.798	0.618	0.494	0.841	0.847	0.8	0.642	0.055	0.124	−0.006	0.158
G_S_mRMR_XGB	0.844	0.729	0.607	0.354	0.814	0.783	0.766	0.576	0.115	0.253	0.031	0.19
G_D_Lasso_DT	0.815	0.568	0.574	0.282	0.808	0.71	0.696	0.346	0.247	0.292	0.098	0.35
G_D_Lasso_RF	0.855	0.722	0.638	0.466	0.826	0.824	0.754	0.659	0.133	0.172	0.002	0.095
G_D_Lasso_XGB	0.84	0.652	0.576	0.32	0.856	0.7	0.798	0.447	0.188	0.256	0.156	0.351
L_S_Lasso_XGB	0.826	0.652	0.56	0.363	0.855	0.755	0.844	0.54	0.174	0.197	0.1	0.304
Lp_D_SVM-RFE_LR_EN	0.806	0.368	0.55	0.001	0.786	0.581	0.706	0.812	0.438	0.549	0.205	−0.106
Lp_S_Boruta_XGB	0.833	0.64	0.591	0.091	0.874	0.646	0.861	0.874	0.193	0.5	0.228	−0.013
Lp_S_mRMR_NB	0.873	0.389	0.554	0.075	0.836	0.55	0.793	0.713	0.484	0.479	0.286	0.08
Lp_S_mRMR_LR	0.872	0.404	0.528	0.006	0.853	0.53	0.804	0.783	0.468	0.522	0.323	0.021
Lp_S_mRMR_LR_EN	0.882	0.49	0.566	0.078	0.849	0.667	0.783	0.862	0.392	0.488	0.182	−0.079
Lp_S_mRMR_RF	0.879	0.44	0.617	0.124	0.881	0.58	0.868	0.805	0.439	0.493	0.301	0.063
Lp_S_mRMR_XGB	0.85	0.427	0.534	0.227	0.864	0.697	0.845	0.871	0.423	0.307	0.167	−0.026
Lp_S_Lasso_XGB	0.852	0.305	0.667	0.073	0.904	0.634	0.907	0.846	0.547	0.594	0.27	0.061