Table 3.
Representation of answers to questions by intensity of side effects.
| P2c | D2c | p | P3c | D3c | p | P4c | D4c | p | |
|---|---|---|---|---|---|---|---|---|---|
| No side-effects reported | |||||||||
| None | 824 (66.3) | 975 (78.5) | <0.001 | 780 (62.8) | 910 (73.3) | 0.002 | 796 (64.1) | 918 (73.9) | 0.003 |
| Reported side-effects | |||||||||
| Mild | 169 (13.6) | 142 (11.4) | 0.126 | 151 (12.2) | 187 (15.1) | 0.050 | 165 (13.3) | 188 (15.1) | 0.221 |
| Moderate | 163 (13.1) | 85 (6.8) | <0.001 | 195 (15.7) | 73 (5.9) | <0.001 | 168 (13.5) | 61 (4.9) | <0.001 |
| Severe | 86 (6.9) | 40 (3.2) | <0.001 | 116 (9.3) | 72 (5.8) | 0.001 | 113 (9.0) | 75 (6.0) | 0.006 |
| Total | 418 | 267 | <0.001 | 462 | 332 | <0.001 | 446 | 324 | <0.001 |
P2c = patient second cycle; D2c = physician second cycle; P3c = patient third cycle; D3c = physician third cycle; P4c = patient fourth cycle; D4c = physician fourth cycle. p-level of statistical significance of patients and physicians based on chi-square test. with zero degrees of freedom (assuming equal frequency of reporting side effects at. expected frequencies).