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. 2021 Sep 17;132(2):1496–1502. doi: 10.1111/jam.15284

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© 2021 The Authors. Journal of Applied Microbiology published by John Wiley & Sons Ltd on behalf of Society for Applied Microbiology.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Antiviral activity of hypochlorous acid (HClO) against severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). Concentrated SARS‐CoV‐2 by polyethylene glycol was treated with (a) 56.3, 113 or 225 ppm of HClO for 0.5 (), 1 (), 3 () or 5 () min, and (b) 11.3 (), 28.1 (), 56.3 () or 113 () ppm of HClO for 10 s followed by determination of virus titer with 50% tissue culture infective dose. All data represent the mean + SD from three independent experiments. Dot line indicates detection limit for experiment. * indicates that values are significantly different between phosphate‐buffered saline (PBS) and each experimental condition

Inline graphic — Antiviral activity of hypochlorous acid (HClO) against severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). Concentrated SARS‐CoV‐2 by polyethylene glycol was treated with (a) 56.3, 113 or 225 ppm of HClO for 0.5 (), 1 (), 3 () or 5 () min, and (b) 11.3 (), 28.1 (), 56.3 () or 113 () ppm of HClO for 10 s followed by determination of virus titer with 50% tissue culture infective dose. All data represent the mean + SD from three independent experiments. Dot line indicates detection limit for experiment. * indicates that values are significantly different between phosphate‐buffered saline (PBS) and each experimental condition