TABLE 2.
Reactivity of human sera to whole cells and recombinant antigens of B. burgdorferi in class-specific ELISA for IgG antibodies
| Study groupa | Total no. of serum samples tested | No. of serum samples positive for reactivity to:
|
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Whole cellsb | p22 | p37 | p39 | p41-Gb | Outer surface proteinsb
|
|||||
| B | C | E | F | |||||||
| EMc | 15 | 15 | 5 | 2 | 8 | 6 | 0 | 6 | 1 | 6 |
| HGE | 18 | 18 | 4 | 3 | 2 | 7 | 2 | 11 | 0 | 7 |
| HGE and LB | 17 | 17 | 6 | 2 | 0 | 8 | 9 | 5 | 0 | 7 |
| Syphilis | 24 | 23 | 2 | 0 | 4 | 3 | 0 | 1 | 0 | 4 |
| Oral infections | 6 | 0 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 0 |
| RA | 7 | 1 | 2 | 0 | 6 | 0 | 0 | 0 | 0 | 0 |
| Normal | 28 | 0 | 4 | 0 | 4 | 1 | 0 | 3 | 0 | 2 |
a
See Table 1, footnotes b to h, for explanations of the study groups.
b
In reanalyses of sera (excluding sera from the HGE groups), some results were the same as those published earlier (23, 24) and are listed here for comparison.
c
All sera were positive in ELISAs for IgG antibodies to whole-cell B. burgdorferi antigen (23).