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Jones methenamine silver-stained renal section of a non-diabetic control rat (A), STZ/NAD (B) and STZ/NAD/L-NAME (C) diabetic rat at week 12. Glomeruli of the diabetic rat show mild mesangial expansion (#) and diffuse thickening of capillary walls (dashed arrow). Tubular lesions manifested as tubular epithelial cell necrosis (asterisk) and tubular atrophy (arrow).
