Table 1.
Altered connectivity between two brain nodes in Top3β−/− mice compared with that in wild mice based on PET/CT analysis.
| Increased Correlation between Two Nodes | Decreased Correlation between Two Nodes | p-Value | ||
|---|---|---|---|---|
| optic_nerve_R | frontal_lobe_R | optic_nerve_R | optic_nerve_L | p < 0.05 |
| optic_nerve_R | midbrain_R | olfactory_bulb_R | anterior_commissure_R | |
| optic_nerve_R | globus_pallidus_L | olfactory_bulb_R | medulla_R | |
| olfactory_bulb_R | subcortical_region_frontal_L | olfactory_bulb_R | striatum_L | |
| anterior_commissure_R | midbrain_R | anterior_commissure_R | ventricle_sum_lat_L | |
| anterior_commissure_R | mamilothalamic_tract_L | occipital_cortex_R | thalamus_R | |
| anterior_commissure_R | corpus_callosum_L | occipital_cortex_R | ventricle_sum_lat_R | |
| frontal_lobe_R | stria_medullaris_thalami_L | subcortical_region_frontal_R | globus_pallidus_R | |
| parietal_temporal_cortex_R | stria_medullaris_thalami_R | subcortical_region_frontal_R | amygdala_R | |
| subcortical_region_parieto_temopal_R | internal_capsule_R | subcortical_region_frontal_R | corpus_callosum_L | |
| fasciculus_retroflexus_R | cerebellum_L | striatum_R | ventricle_sum_sup_L | |
| fasciculus_retroflexus_R | left_pons_L | internal_capsule_R | hypothalamus_L | |
| fasciculus_retroflexus_R | midbrain_L | mammilothalamic_R | corpus_callosum_L | |
| fornix_R | internal_capsule_R | amygdala_R | corpus_callosum_L | |
| globus_pallidus_R | internal_capsule_R | medulla_R | hippocampus_L | |
| stria_medullaris_thalami_R | amygdala_R | pons_R | left_amygdala_L | |
| midbrain_R | corpus_callosum_L | cerebellum_R | corpus_callosum_L | |
| amygdala_R | olfactory_bulb_L | ventricle_sum_sup_R | corpus_callosum_L | |
| medulla_R | mamilothalamic_tract_L | subcortical_region_parieto_temopal_L | frontal_lobe_L | |
| ventricle_sum_sup_R | olfactory_bulb_L | |||
| ventricle_sum_lat_L | globus_pallidus_L | |||
| cerebellum_L | medulla_L | |||
| cerebellum_L | internal_capsule_L | |||
| cerebellum_L | subcortical_region_parieto_temopal_L | |||
| cerebellum_L | frontal_lobe_L | |||
| cerebellum_L | olfactory_bulb_L | |||
| medulla_L | internal_capsule_L | |||
| hippocampus_L | midbrain_L | |||
| globus_pallidus_L | striatum_L | |||
| subcortical_region_frontal_L | anterior_commissure_L | |||
| optic_nerve_R | globus_pallidus_L | |||
| amygdala_R | olfactory_bulb_L | |||
| Cerebellum_L | olfactory_bulb_L | p < 0.01 | ||
| Optic_nerve_R | globus_pallidus_L | p < 0.005 | ||
| amygdala_R | olfactory_bulb_L | |||