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Immunization with recombinant Tp0136 or Tp0663 protein attenuated lesion development. (A) Lesion diameters were monitored over 21 days in the control, Tp0136-immunized or Tp0663-immunized animals following T. pallidum challenge. (B) Indurated lesions from eight locations on the backs of the rabbits were taken 21 days post-intradermal challenge with T. pallidum (Nichols strain).
