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. 2021 Nov 25;12:723173. doi: 10.3389/fimmu.2021.723173

Figure 6.

Figure 6

Effect of L. casei ATCC 393 and VIP receptor antagonist (aVIP) on microbial community in cecum of mice challenged by ETEC K88. (A) α-diversity analysis. (B) PCA plot of microbial community composition showed the compositional variance. (C) Differences in composition of microbial communities at phylum level. (D) Differences in composition of microbial communities at genus level. (E) LEfSe analysis of microbiota. All data are presented as the mean ± S.E.M. (n=4). * P < 0.05, ** P < 0.01. aVIP means the mice were intraperitoneally (i.p.) injected with aVIP. L means the mice orally received L. casei ATCC 393. ETEC K88 means the mice orally received ETEC K88.