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. 2021 Nov 25;11:774445. doi: 10.3389/fonc.2021.774445

Table 2.

Characteristics of individual patients.

No. Age(year) Sex ECOG PS Cancer type Sites of metastasis when on treatment KRAS/BRAF mutation status MMR or MSI status Combining regimen No. of cycles Response
1 62 F 0 Rectum Abdomino-pelvic cavity Wt pMMR/MSS Cam+Rego+XELOX 17 PR
2 68 F 1 Rectum Liver, lung, kidney, peritoneal cavity, RPLN Wt pMMR/MSS Cam+Rego+XELOX 4 PD
3 45 F 1 Right-sided colon Peritoneal cavity, RPLN, abdominal aortic LN KRAS Mt pMMR/MSS Cam+Rego+XELOX 8 SD
4 70 M 0 Right-sided colon Liver, lung, peritoneal cavity KRAS Mt pMMR/MSS Cam+Rego+XELOX 15 PR
5 58 M 0 Right-sided colon Liver Wt pMMR/MSS Cam+Rego+XELOX 14 PR
6 55 M 0 Rectum Lung Wt pMMR/MSS Cam+Rego+XELOX 15 PR
7 53 F 0 Rectum Liver KRAS Mt pMMR/MSS Cam+Bev+XELOX 4 PR
8 64 M 0 Right-sided colon Liver, lung, peritoneal cavity Unknown Unknown Cam+Bev+XELOX 18 PR
9 86 F 2 Right-sided colon Abdomino-pelvic cavity Unknown Unknown Cam+Bev+XELOX 2 SD
10 78 M 0 Left-sided colon Liver Wt pMMR/MSS Cam+Bev+XELOX 4 PR
11 65 M 0 Left-sided colon Liver Wt pMMR/MSS Cam+Bev+XELOX 7 PR
12 64 M 0 Rectum Lung Wt pMMR/MSS Cam+Bev+XELOX 8 PR
13 69 M 0 Left-sided colon Peritoneum KRAS Mt pMMR/MSS Cam+Bev+XELOX 6 PR
14 70 M 1 Rectum Pelvic cavity Unknown pMMR/MSS Cam+Bev+XELOX 10 SD
15 66 F 0 Left-sided colon Liver KRAS Mt dMMR/MSI-H Cam+Bev+XELOX 14 PR
16 62 F 0 Right-sided colon Adrenal gland, peritoneal cavity, peritoneum, lymph nodes Unknown pMMR/MSS Cam+Bev+XELOX 6 SD
17 43 F 0 Left-sided colon Liver Wt pMMR/MSS Cam+Bev+XELOX 8 PR
18 55 F 1 Right-sided colon Liver, peritoneum, peritoneal cavity Unknown pMMR/MSS Cam+Bev+XELOX 12 PR
19 52 M 0 Rectum Lung KRAS Mt pMMR/MSS Cam+Bev+XELOX 8 SD
20 57 F 1 Rectum Liver, peritoneal cavity, bilateral ovarian KRAS Mt pMMR/MSS Cam+Bev+XELOX 11 PR
21 67 M 2 Rectum Liver, peritoneum Unknown Unknown Cam+Bev+XELOX 5 PR
22 63 M 0 Left-sided colon Liver, lymph nodes KRAS Mt pMMR/MSS Cam+Bev+XELOX 5 PR
23 54 F 1 Rectum Liver Wt pMMR/MSS Cam+Bev+XELOX 4 PR
24 77 F 1 Rectum Lung, bone, cervical and pelvic wall Wt pMMR/MSS Cam+Bev+XELOX 3 PR
25 76 M 1 Left-sided colon Abdominal wall, abdomino-pelvic cavity Wt pMMR/MSS Cam+Bev+XELOX 8 SD

ECOG PS, Eastern Cooperative Oncology Group performance status; F, female; M, male; Mt, mutant; Wt, wild-type; Cam, camrelizumab; Bev, bevacizumab; Rego, regorafenib; XELOX, capecitabine and oxaliplatin; PR, partial response; SD, stable disease; PD, progression of disease; RPLN, retroperitoneal lymph node.