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. 2021 Nov 25;11:774445. doi: 10.3389/fonc.2021.774445

Table 4.

Adverse events.

Adverse event Grade 1-2, N (%) Grade ≥3, N (%) Any grade, N (%)
Neutropenia 8 (32) 1 (4) 9 (36)
Decreased platelet count 6 (24) 1 (4) 7 (28)
Nausea and Vomiting 1 (4) 1 (4) 2 (8)
Liver dysfunction 2 (8) 2 (8) 4 (16)
Hand-foot syndrome 4 (16) 3 (12) 7 (28)
Gastric hemorrhage 0 1 (4) 1 (4)
Diarrhea 1 (4) 1 (4) 2 (8)
Fever 2 (8) 1 (4) 3 (12)
Hyperthyroidism 4 (16) 0 4 (16)
Hypothyroidism 2 (8) 0 2 (8)
Hyperglycemia 1 (4) 1 (4) 2 (8)
RCCEP 8 (32) 0 8 (32)
Vision changes 1 (4) 0 1 (4)
Myocarditis 2 (8) 0 2 (8)
Infusion-related reactions 2 (8) 0 2 (8)
ALL 16 (64) 8 (32) 18 (72)

RCCEP, reactive cutaneous capillary endothelial proliferation.