Table 2.

Structural data for ENPs (represented by peak 2 and 3) determined by dynamic (DLS) and static light scattering (SLS) measurements for patients with ovarian cancer (OC): the mean hydrodynamic radius for peaks in the size distributions at an angle θ = 90° (R_h,90), hydrodynamic radius extrapolated to θ = 0° (R_h,0), radius of gyration (R_g), the shape parameter $\rho (=R_g/R_h)$, and the contribution of by peak 2 (or 3) particles to the total scattering intensity at θ = 90° (% I_tot,90). The R_h values in bold and italic were obtained with η_o ≈ 1.2 mPa s⁻¹.

		Rh,90/nm			Angular Dependency (Peak 2 or 3)			Peak 2 or 3
Patient	Sample	Peak 1	Peak 2	Peak 3	Rh,0/nm	Rg/nm	ρ	% Itot,90 (Peak 2 or 3)
OC1 #	plasma	3.7	24	70
	ascites	7.0	27	80
	ascitesF	/	29	/
OC2	plasma	5.4	24	/	24.3	24.8	1.02	88
	ascites	4.2	21	/	22.9	23.7	1.04	77
	ascitesF	4.0	20	/	20.2	20.4	1.01	76
OC3	plasma	4.4	17	46 &	25.4	26.2	1.03	63
	ascites	7.2	17	/	20.6	21.1	1.03	61
	ascitesF	4.6	20	/	21.9	25.5	1.16	77
OC4	plasma	2.7	22	/	24.7	25.5	1.03	64
	ascites	2.9	17	102 &	21.9	21.2	0.97	51
	ascitesF	4.1	24	/	21.2	21.8	1.03	56
OC5	plasma	4.7	23	/	34.0	34.0	1.00	50
	ascites	3.7	20	/	34.2	36.3	1.06	46
	ascitesF	4.1	24	/	46.8	53.4	1.14	43
OC6	plasma	5.1	26	/	24.6	24.6	1.00	74
	ascites	4.7	21	/	28.0	29.2	1.04	49
	ascitesF	4.0	18		22.9	22.7	0.99	63
				68	150	160	1.07	13
	ascites *	5.6	27		28.7	29.0	1.01	18
				150	143	165	1.10	15
	ascitesF *	3.8	14		17.0	36.0	(~2.1)	56
				62	101	115	1.14	34
OC7	plasma *	4.1	20		~21	~32	(~1.5)	76
				173	188	185	0.99	11
	ascites *	3.2	16		26.9	28.4	1.05	71
				83	203	230	1.13	13
	ascitesF *	4.5	20		22.3	33.4	(~1.5)	75
				90	105	115	1.09	13

^# for patient OC1 only preliminary DLS measurements at θ = 90° were collected; * analysis of thawed samples; ascitesF = filtered ascites; ^& for these particles, the analysis of angular dependency could not be performed; values in bold and italic in the “angular dependency” column are for peak 3.