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. 2021 Nov 23;22(23):12659. doi: 10.3390/ijms222312659

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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IL-23Ap19- and/or EBI3-including cytokines in epidermal keratinocytes. IL-23Ap19 and EBI3 were detected by qPCR, ELISA, and LC-Ms/Ms. IL-27Ap28 and IL-12Ap35 were undetected by qPCR. IL-23(p19/p40), IL-27(p28/EBI3), IL-35(p35/EBI3), and IL-39(p19/EBI3) were undetected by ELISA or LC-Ms/Ms. This result raises the possibility that IL-23Ap19 and EBI3 produced from epidermal keratinocytes exist as a monomer or homopolymer, such as a homodimer or homotrimer. ?, Not yet detected and possibility.