The expression of chemokine receptors on splenic leukocytes is not affected by PCSK9 overexpression in vivo, except in T-cells. The expression of chemokine receptors was measured using flow cytometry and represented using geometric mean (Geo.Mean) in splenic leukocytes (A), classical monocytes (B), non-classical monocytes (C), neutrophils (D), B cells (E), and T cells (F) of PCSK9 over-expressing mice (n = 8) and compared to control mice (n = 8). Bar graphs are a representation of mean ± SEM. ** p < 0.01. The statistical difference between the groups was calculated using 2-way ANOVA tests in GraphPad Prism.