Table 4.

Drugs that can effectively be removed by CytoSorb^® or in which a relevant decrease of serum concentrations must be expected (modified from [62]).

	Drug Group	Active Pharmaceutical Substances	References
positive effect likely	Antiarrhythmics	Amitriptyline	[145]
		Flecainide	[146]
		Digoxin	[141]
		Digitoxin	[147]
	Antidepressant	Amitryptilin	[145,148]
	Anticonvulsants	Carbamazepine	[141]
		Valproic Acid
		Phenytoin
	Beta Blocker	Bisoprolol	[148]
	Calciumchannel blockers	Amlodipine	[148]
		Verapamil	[149]
	Hypnotics and sedatives	Phenobarbital	[141]
	Psychotropic drugs	Quetiapine	[143]
		Venlafaxine	[150]
		3,4-Methylenedioxy-methamphetamine (MDMA, “Ecstasy”)	[151]
	Toxins	Aflatoxine	[32,152]
		Toxic Shock Syndrome toxin-1 (TSST-1)	[32]
		Viper Snake Venom	[153]
positive or negative effect likely (according to the indication)	Anticoagulants	Dabigatran	[154]
		Edoxaban	[155]
		Rivaroxaban	[59,156]
		Ticagrelor	[59,139,144,156]
	Contrast agents	Iodixanol Iohexol	[157,158]
	Immunosuppressives	Tacrolimus Cyclosporine	[141]
negative effect likely	Antibiotics	Amikacin, Vancomycin, Tobramycin, Gentamicin, Ciprofloxacin, Meropenem, Piperacillin, Flucloxacillin, Imipenem, Teicoplanin, Linezolid	[61,63,141,159,160]
	Antimycotics	Fluconazole, Voriconazole	[63]