Table 3.
Group comparison of hippocampal subfields volume.
| HC (n = 20) | T2DM (n = 30) | F value | P value | q value | partial eta 2 | |
|---|---|---|---|---|---|---|
| Left hippocampal tail | 579.05 ± 77.01 | 552.49 ± 54.49 | 1.757 | 0.192 | 0.263 | 0.038 |
| Left subiculum | 473.15 ± 54.25 | 430.64 ± 33.78 | 10.473 | 0.002 | 0.017* | 0.192 |
| Left CA1 | 641.28 ± 53.76 | 607.83 ± 65.95 | 2.182 | 0.147 | 0.225 | 0.047 |
| Left hippocampal fissure | 146.95 ± 28.34 | 153.76 ± 26.71 | 1.45 | 0.235 | 0.306 | 0.032 |
| Left presubiculum | 334.09 ± 41.40 | 310.76 ± 30.03 | 4.374 | 0.042 | 0.084 | 0.090 |
| Left parasubiculum | 59.89 ± 12.20 | 54.35 ± 10.50 | 3.256 | 0.078 | 0.127 | 0.069 |
| Left molecular layer | 588.10 ± 44.03 | 547.13 ± 44.22 | 8.146 | 0.007 | 0.020* | 0.156 |
| Left GC-ML-DG | 300.92 ± 27.88 | 274.62 ± 24.96 | 8.877 | 0.005 | 0.019* | 0.168 |
| Left CA2/3 | 194.59 ± 21.62 | 191.19 ± 21.02 | 0.092 | 0.763 | 0.763 | 0.002 |
| Left CA4 | 257.06 ± 22.77 | 236.76 ± 20.68 | 6.922 | 0.012 | 0.028* | 0.136 |
| Left fimbria | 83.20 ± 19.23 | 63.92 ± 18.05 | 11.608 | 0.001 | 0.013* | 0.209 |
| Left HATA | 56.37 ± 5.25 | 54.76 ± 6.51 | 0.113 | 0.739 | 0.769 | 0.003 |
| Left whole hippocampus | 3567.70 ± 266.34 | 3324.40 ± 239.99 | 9.461 | 0.004 | 0.017* | 0.177 |
| Right hippocampal tail | 602.24 ± 74.05 | 589.51 ± 56.89 | 0.168 | 0.684 | 0.741 | 0.004 |
| Right subiculum | 469.78 ± 49.06 | 443.72 ± 34.80 | 3.395 | 0.072 | 0.125 | 0.072 |
| Right CA1 | 691.99 ± 57.26 | 646.84 ± 62.27 | 4.097 | 0.049 | 0.091 | 0.085 |
| Right hippocampal fissure | 153.39 ± 24.97 | 161.29 ± 22.34 | 1.96 | 0.168 | 0.243 | 0.043 |
| Right presubiculum | 313.72 ± 40.19 | 301.59 ± 28.59 | 0.751 | 0.391 | 0.462 | 0.017 |
| Right parasubiculum | 55.45 ± 11.18 | 52.08 ± 9.71 | 0.616 | 0.437 | 0.494 | 0.014 |
| Right molecular layer | 614.52 ± 48.97 | 573.55 ± 44.29 | 6.682 | 0.013 | 0.028* | 0.132 |
| Right GC-ML-DG | 317.47 ± 29.96 | 289.77 ± 24.32 | 9.856 | 0.003 | 0.020* | 0.183 |
| Right CA2/3 | 220.62 ± 28.39 | 207.70 ± 24.38 | 1.226 | 0.274 | 0.339 | 0.027 |
| Right CA4 | 271.65 ± 26.29 | 248.70 ± 20.16 | 8.596 | 0.005 | 0.016* | 0.163 |
| Right fimbria | 81.72 ± 18.89 | 60.93 ± 17.93 | 18.993 | <0.001 | <0.026* | 0.302 |
| Right HATA | 62.69 ± 7.50 | 56.77 ± 5.34 | 9.852 | 0.003 | 0.016* | 0.183 |
| Right whole hippocampus | 3701.86 ± 286.18 | 3471.11 ± 234.58 | 7.553 | 0.009 | 0.023* | 0.147 |
Adjusted age, sex, education, and eTIV. CA, cornu ammonis; GC, granular cell; ML, molecular layer; DG, dentate gyrus; HATA, hippocampus amygdala transition area. Correction adjusted P value (q value) < 0.05 had statistical significance.
*
Correction adjusted P value (q value) < 0.05.