Figure 1.

Evaluation of the anxiety-like behaviour on the OFT test in the early stress stage. CON and 3d CUMS (n = 10 animals per group) rats were subjected to the OFT for 5 min. (a) Number of crosses between inner and outer zone. (b) Total number of fecal boli deposits. The number of defecations was counted by the researcher after the rats were removed. (c) Rearing behaviour. The statistical comparisons among groups were conducted using Student’s t test; the statistically significant p-values versus CON (p < 0.05) are highlighted with an asterisk (*).