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. 2021 Dec 1;22(23):13022. doi: 10.3390/ijms222313022

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Numbers of mesangial proliferative glomeruli in 50 observed glomeruli in mice treated with P. gingivalis or saline (control). Glomeruli were evaluated by PAS staining. Each group consists of 10 mice. Numbers of mesangial proliferative glomeruli in 50 observed glomeruli in mice treated with P. gingivalis were significantly higher than those in control mice at day 14 (p < 0.01), at day 28 (p < 0.05), at day 42 (p < 0.05) and at day 56 (p < 0.01) after treatment of bacteria.