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. 2021 Nov 25;22(23):12729. doi: 10.3390/ijms222312729

Figure 4.

Figure 4

Alterations of the colonic myeloperoxidase (MPO) enzyme activity (a) and expression (b) following H2S donor administration in TNBS-induced rat colitis. Absolute control (no treatment); EtOH (50% ethanol, the solvent of TNBS); TNBS (2,4,6-trinitrobenzenesulfonic acid enema); H2S donor (TNBS + 18.75 µM/kg/day Lawesson’s reagent); CMC (TNBS + 0.5% carboxymethylcellulose, the vehicle of Lawesson’s reagent); SASP (TNBS + 50 mg/kg/day sulfasalazine, as a positive control). Results are presented as mean + S.E.M.; n = 5–11/group; one-way ANOVA, Holm–Sidak post hoc test, ## p < 0.001 absolute control vs. TNBS; * p < 0.05, ** p < 0.001 TNBS vs. TNBS + treatments; & p < 0.05, && p < 0.001 absolute control vs. EtOH.