TABLE 3.

Short treatment of HSV isolates with zinc salts^a

Expt. no., treatment, and HSV type, isolate no.	Mean ± SD PFU		% Inactivation
	Mock-treated HSV	Zn-treated HSV
Expt 1
Zn gluconate + glycine
HSV-1, 2	215 ± 34	158 ± 18	27
HSV-1, 14	107 ± 12	70 ± 9	35
HSV-1, 18	224 ± 28	179 ± 13	20
HSV-2, 8	45 ± 6	34 ± 7	24
HSV-2, 16	159 ± 32	99 ± 9	38
Zn lactate
HSV-1, 2	191 ± 29	147 ± 22	23
HSV-1, 14	131 ± 25	74 ± 18	44
HSV-1, 18	180 ± 31	151 ± 14	16
HSV-2, 8	40 ± 7	23 ± 5	43
HSV-2, 16	238 ± 31	106 ± 18	55
Expt 2
Zn acetate
HSV-1, 2	303 ± 5	234 ± 36	23
HSV-1, 18	36 ± 5	38 ± 6	−6
HSV-2, 8	275 ± 49	175 ± 11	36
HSV-2, 19	234 ± 19	145 ± 25	38
HSV-2, 20	75 ± 9	69 ± 8	8
Zn sulfate
HSV-1, 2	295 ± 73	151 ± 25	49
HSV-1, 18	40 ± 8	21 ± 1	48
HSV-2, 8	259 ± 10	170 ± 24	34
HSV-2, 19	213 ± 40	140 ± 39	34
HSV-2, 20	46 ± 4	37 ± 5	20

^aTreatment was for 5 min at 37°C with 50 mM Zn. All plaque counts are averages for three wells.