Table 1.
Systemic leukocyte counts.
PMNL | MNL | Total Leukocytes | |
---|---|---|---|
Sham | 1.2 ± 0.2 | 5.3 ± 1.9 | 6.5 ± 1.8 |
Vehicle + CLP | 0.6 ± 0.3 # | 2.0 ± 0.8 # | 2.6 ± 1.1 # |
ABR + CLP | 1.3 ± 0.5 * | 3.2 ± 0.7 | 4.6 ± 0.9 * |
Mice were pre-treated with intraperitoneal injections of the vehicle or ABR-238901 (10 mg/kg) 1 h before Sham or CLP operation. Blood was collected from animals 24 h after CLP induction and leukocytes were identified as polymorphonuclear leukocytes (PMNL) and monomorphonuclear (MNL). Data are presented with mean ± SEM, 106 cells/mL. # p < 0.05 vs. Sham, * p < 0.05 vs. Vehicle, n = 5.