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. 2021 Dec 3;22(23):13084. doi: 10.3390/ijms222313084

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effects of O-1602 on the expression of adhesion molecules in THP-1 cells. THP-1 cells were treated with the indicated concentration of O-1602 for 24 h. The mRNA expression of adhesion molecules was analyzed by RT-PCR. (A) Representative RT-PCR images. (B) Histograms showing the relative mRNA levels. (C) Representative flow cytometry images of Mac-1 protein. (D) Histograms showing relative Mac-1 protein levels. The results are presented as the mean ± SEM of three independent experiments. Statistical significance: ** p < 0.01, *** p < 0.001 vs. untreated control cells.