Table 1.
Protein Families Most Often Encoded in the Extended Gene Type IV Neighborhoods
| Cluster/family ID | Weighted frequency | Comment |
|---|---|---|
| MMseq 0.5 clusters | ||
| CLUSTER_52 | 28.7 | CysH-like |
| CLUSTER_53 | 28.7 | ADP phosphoribosyltransferase VIP2-like |
| CLUSTER_28 | 22.3 | MoxR-like ATPase |
| CLUSTER_141 | 21.3 | Unknown |
| CLUSTER_40 | 19.4 | MoxR associated zincin metallopeptidase fused vWFA domain |
| CLUSTER_33 | 18.8 | DNA2-like Helicase |
| CLUSTER_256 | 13.7 | Uncharacterized DUF1870 |
| CLUSTER_46 | 13.4 | CysH-like |
| CLUSTER_119 | 11.8 | MoxR associated (precursor releasing small C-terminal peptide) |
| CLUSTER_126 | 9.4 | MoxR associated (precursor releasing small C-terminal peptide) |
| CDD assignments | ||
| COG0175 | 103.17 | CysH-like |
| COG1199 | 76.0 | DinG |
| COG1674 | 33.5 | DNA segregation ATPase FtsK/SpoIIIE |
| COG1396 | 30.7 | XRE-family HTH domain |
| COG4974 | 29.7 | Site-specific recombinase XerD |
| COG1475 | 27.9 | Chromosome segregation protein Spo0J, contains ParB-like nuclease domain |
| COG0714 | 26.7 | MoxR-like ATPase |
| COG1192 | 24.4 | Chromosome segregation ATPase ParA |
| COG2801 | 24.0 | Transposase InsO |
| COG1028 | 24.0 | NAD(P)-dependent dehydrogenase |
| cd00093 | 23.3 | Helix-turn-helix XRE-family like proteins. |
| COG0582 | 20.7 | Site-specific recombinase XerC |
| pfam07510 | 20.5 | Protein of unknown function (DUF1524), predicted His-Me finger endonuclease |
| COG3864 | 20.4 | Zincin metal-dependent peptidase, MoxR associated |