Current flow through the spine generated by transcutaneous spinal cord stimulation with the paraspinal electrode placed over the T11 and T12 spinal processes and reference electrodes over the lower abdomen (not shown). (A) Computer simulation of the current flow in the sagittal plane at the level of the stimulating paraspinal electrode. Shown are the results of a section of the three-dimensional model in a midsagittal layer with a thickness of 2 mm. Various anatomical structures with tissue-specific electrical conductivities were considered in the model, including paraspinal muscles, vertebral bones, the vertebral canal with the dural sac containing the spinal cord, and intervertebral discs. Only the mid-sagittal cross-sectional areas of the vertebrae are displayed. The current largely crosses the spine via the soft tissues in-between the vertebrae. The density of the lines is proportional to the local current densities. Scaling: the paraspinal electrode (vertical red rectangle on the far left side) represents 5 cm. Computer simulation model from [15,17]. (B) Midsagittal bone window CT scan, case courtesy of Assoc Prof Frank Gaillard, Radiopaedia.org, rID: 43822. The white box indicates the approximate anatomic region shown in (A).