Table 1.
Resuscitation characteristics in pre- vs. intra-COVID-19 periods.
| Outcome | No. of Studies | Events/Participants | Events | Heterogeneity between Trials |
p-Value for Differences across Groups |
|||
|---|---|---|---|---|---|---|---|---|
| Pre-COVID-19 Period |
COVID-19 Period |
OR | 95%CI | p-Value | I2 Statistic |
|||
| Cardiac arrest location at home | 17 | 19,493/26,948 (73.3%) |
19,860/25,625 (77.5%) |
0.74 | 0.65 to 0.84 | <0.001 | 86% | <0.001 |
| Witnessed arrest | 21 | 16,798/37,960 (44.3%) |
12,416/26,994 (46.0%) |
1.04 | 0.96 to 1.11 | <0.001 | 62% | 0.34 |
| Bystander CPR | 23 | 17,092/38,741 (44.1%) |
12,586/27,248 (46.2%) |
1.00 | 0.88 to 1.14 | <0.001 | 90% | 1.0 |
| Bystander AED use | 14 | 1704/21,089 (8.1%) |
1221/19,964 (6.1%) |
1.35 | 1.25 to 1.46 | <0.001 | 73% | <0.001 |
| Advanced airway management | 10 | 9707/20,839 (46.6%) |
8166/12,549 (65.1%) |
1.20 | 0.82 to 1.76 | <0.001 | 97% | 0.34 |
| Endotracheal intubation |
8 | 6605/20,058 (32.9%) |
3838/10,277 (37.3%) |
1.91 | 1.37 to 2.68 | <0.001 | 95% | <0.001 |
| Supraglottic airway devices | 8 | 2926/19,410 (15.1%) |
3743/10,519 (35.6%) |
0.67 | 0.42 to 1.05 | <0.001 | 97% | 0.08 |
| Mechanical chest compression |
3 | 486/2629 (18.5%) |
557/2137 (26.1%) |
0.97 | 0.50 to 1.88 | <0.001 | 92% | 0.93 |
| Targeted temperature management | 3 | 81/2920 (2.8%) |
44/2638 (1.7%) |
1.62 | 0.85 to 3.07 | 0.07 | 63% | 0.14 |
Legend: AED: automated external defibrillation; CI: confidence interval; CPR: cardiopulmonary resuscitation; OR: odds ratio. Note: Not all outcomes were reported in every study. “No. of studies” refers to the studies included in the analysis for the particular outcome.