TABLE 3.
Effect of irradiation on coding end deletions in wild-type and SCID cellsa
| Cell line | No. of deletions | Irradiation
|
|
|---|---|---|---|
| None [no. (%)] | 100 cGy [no. (%)] | ||
| VL3-3M2 | 0 | 11 (39) | 13 (19) |
| 1–5 | 12 (43) | 41 (61) | |
| 6–10 | 5 (18) | 11 (16) | |
| 11–20 | 0 (0) | 3 (4) | |
| 21–30 | 0 (0) | 0 (0) | |
| >30 | 0 (0) | 0 (0) | |
| Avg, SD | 4.4, 2.5 | 4.9, 3.2 | |
| LK6.2 | 0 | 17 (47) | 30 (29) |
| 1–5 | 10 (27) | 19 (19) | |
| 6–10 | 2 (6) | 15 (19) | |
| 11–20 | 5 (14) | 14 (16) | |
| 21–30 | 2 (6) | 9 (12) | |
| >30 | 0 (0) | 5 (5) | |
| Avg, SD | 10.2, 8.9 | 13.4, 12.4 | |
a
The number and percent of coding ends with the indicated numbers of nucleotides deleted are shown for each group. Shown is a summary of data from Fig. 1 and 2. Since the time of irradiation (relative to transfection) did not alter the distribution of coding end deletions, all the data for irradiated cells from Fig. 1 and 2 have been pooled.