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. 2021 Dec 3;22(23):13106. doi: 10.3390/ijms222313106

Figure 1.

Figure 1

Survival and differentiation of transplanted NPCs eight weeks after severe cervical SCI. (A) Representative image of an NPC animal spinal cord cross-section at 10× magnification depicting the spatial distribution of transplanted NPCs (GFP+/DAPI+), NPC-derived neurons (GFP+/DAPI+/NeuN+) and NPC-derived oligodendrocytes (GFP+/DAPI+/APC+; scale bar = 500 µm). (B) Mean number of surviving NPCs (GFP+), NPC-derived mature neurons (GFP+/NeuN+), NPC-derived mature oligodendrocytes (GFP+/APC+) and undifferentiated NPCs (GFP+/Nestin+) in the injured spinal cord of animals in the NPC group (group 1; n = 8 animals). (C) Colocalization (green arrows) of DAPI, GFP and APC, indicating surviving, viable and mature NPC-derived oligodendrocytes and of (D) DAPI, GFP and NeuN, indicating surviving, viable and mature NPC-derived neurons in an NPC animal at 40× magnification (scale bar = 100 µm).