Table 4.
Demographics and Clinical Characteristics after Gender and Age Matching for Groups of Glaucomatous Subjects and Control Subjects.
| A vs. B N = 288:32 |
A vs. C N = 314:314 |
B vs. C N = 62:310 |
p-Value | ||||||
|---|---|---|---|---|---|---|---|---|---|
| a | b | c | |||||||
| Age | 44.7 ± 13.9 | 48.6 ± 15.7 | 47.7 ± 14.4 | 48.2 ± 12.9 | 46.9 ± 12.2 | 50.6 ± 14.1 | 0.12 | 0.52 | 0.33 |
| <40 | 112 (38.9%) | 9 (28.1%) | 81 (25.8%) | 95 (30.2%) | 15 (24.2%) | 75 (24.2%) | 0.24 | 0.95 | 0.20 |
| 40–60 | 142 (49.3%) | 18 (56.3%) | 177 (56.4%) | 150 (47.8%) | 40 (64.5%) | 163 (52.6%) | |||
| ≥60 | 34 (11.8%) | 5 (15.6%) | 56 (17.8%) | 69 (22.0%) | 7 (11.3%) | 72 (23.2%) | |||
| Gender | 1.00 | 1.00 | 0.23 | ||||||
| Male | 72 (25.0%) | 8 (25.0%) | 156 (49.7%) | 156 (49.7%) | 43 (69.3%) | 190 (61.3%) | |||
| Female | 216 (75.0%) | 24 (75.0%) | 158 (50.3%) | 158 (50.3%) | 19 (30.7%) | 120 (38.7%) | |||
| SBP | 122.5 ± 17.7 | 130.3 ± 18.4 | 126.2 ± 18.4 | 125.9 ± 17.5 | 129.5 ± 16.0 | 129.0 ± 18.6 | 0.03 | 0.85 | 0.82 |
| DBP | 72.0 ± 12.0 | 76.8 ± 13.0 | 75.4 ± 12.0 | 74.5 ± 11.7 | 78.6 ± 12.5 | 76.0 ± 12.3 | 0.03 | 0.35 | 0.13 |
| MAP | 88.9 ± 13.0 | 94.7 ± 13.5 | 92.4 ± 13.2 | 91.7 ± 12.5 | 95.6 ± 12.7 | 93.6 ± 13.1 | 0.02 | 0.51 | 0.28 |
| HR | 79.4 ± 12.4 | 75.5 ± 9.8 | 78.8 ± 12.3 | 74.7 ± 11.5 | 74.9 ± 10.1 | 75.5 ± 12.3 | 0.08 | <0.001 | 0.71 |
| TG | 105.7 ± 69.9 | 102.3 ± 45.6 | 122.7 ± 87.1 | 113.1 ± 49.7 | 108.6 ± 45.0 | 116.9 ± 57.2 | 0.64 | 0.27 | 0.52 |
| HDL | 55.9 ± 13.5 | 55.2 ± 12.4 | 52.4 ± 14.1 | 52.5 ± 14.8 | 52.0 ± 11.7 | 50.4 ± 15.5 | 0.77 | 0.96 | 0.63 |
| LDL | 113.7 ± 32.8 | 115.2 ± 35.1 | 113.6 ± 34.1 | 109.1 ± 29.1 | 119.2 ± 27.4 | 113.4 ± 31.7 | 0.89 | 0.35 | 0.47 |
| AC sugar | 94.1 ± 14.3 | 93.4 ± 8.1 | 96.9 ± 14.1 | 100.3 ± 19.8 | 95.4 ± 8.1 | 104.2 ± 22.5 | 0.70 | 0.12 | 0.001 |
| HbA1c | 6.0 ± 0.7 | 5.1 ± 0.3 | 6.0 ± 0.5 | 6.1 ± 1.1 | 5.4 ± 0.6 | 6.1 ± 0.9 | 0.02 | 0.33 | 0.01 |
| ALT | 20.2 ± 17.1 | 32.0 ± 21.9 | 22.2 ± 11.9 | 23.8 ± 16.2 | 31.1 ± 21.7 | 25.7 ± 18.3 | 0.03 | 0.38 | 0.18 |
| Creatinine | 0.9 ± 1.2 | 0.8 ± 0.2 | 1.0 ± 1.5 | 0.9 ± 0.8 | 0.9 ± 0.2 | 0.9 ± 0.8 | 0.49 | 0.47 | 0.27 |
| eGFR | 100.9 ± 21.3 | 99.2 ± 16.6 | 95.0 ± 21.4 | 95.9 ± 21.2 | 97.9 ± 17.7 | 93.0 ± 21.2 | 0.37 | 0.71 | 0.26 |
| Uric Acid | 5.1 ± 1.3 | 5.3 ± 1.3 | 5.7 ± 1.6 | 5.9 ± 1.3 | 5.9 ± 1.3 | 6.0 ± 1.4 | 0.51 | 0.46 | 0.85 |
Group A, control eyes; Group B, pre-perimetric glaucoma eyes; Group C, glaucoma eyes; a p-value, A vs. B; b p-value, A vs. C; c p-value, B vs. C; Unit. Age (years); SBP (mmHg); DBP (mmHg); MAP (mmHg); HR (/min); TG (mg/dL); HDL (mg/dL); LDL (mg/dL); AC sugar (mg/dL); HbA1c (%); ALT (U/L); Creatinine (mg/dL); eGFR (mL/min/1.73 m2); Uric Acid (mg/dL); Abbreviations. SBP, systolic blood pressure; DBP, diastolic blood pressure; MAP, mean arterial pressure; HR, heart rate; TG, triglyceride; HDL, high-density lipoprotein (cholesterol); LDL, low-density lipoprotein (cholesterol); ALT, aspartate aminotransferase; eGFR, estimated glomerular filtration rate.